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Πλοήγηση ανά Συγγραφέα "Markopoulou, K."

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    • Abnormal serum concentrations of proteins in Parkinson's disease 

      Goldknopf, I. L.; Bryson, J. K.; Strelets, I.; Quintero, S.; Sheta, E. A.; Mosqueda, M.; Park, H. R.; Appel, S. H.; Shill, H.; Sabbagh, M.; Chase, B.; Kaldjian, E.; Markopoulou, K. (2009)
      Blood serum was used to identify protein biomarkers for diagnosis of Parkinson's disease (PD) using analytically validated quantitative 2D-gel electrophoresis, and single variable and multivariate statistics. Using banked ...

    • Acute Disseminated Encephalomyelitis With Bilateral Thalamic Necrosis 

      Dardiotis, E.; Kountra, P.; Kapsalaki, E.; Protogerou, G.; Markopoulou, K. (2009)
      Acute disseminated encephalomyelitis is a monophasic inflammatory demyelinating disease of the central nervous system involving the white matter, and to a lesser extent, the gray matter. Bilateral thalamic lesions have ...

    • Alpha-synuclein repeat variants and survival in parkinson's disease 

      Chung, S. J.; Biernacka, J. M.; Armasu, S. M.; Anderson, K.; Frigerio, R.; Aasly, J. O.; Annesi, G.; Bentivoglio, A. R.; Brighina, L.; Chartier-Harlin, M. C.; Goldwurm, S.; Hadjigeorgiou, G.; Jasinska-Myga, B.; Jeon, B. S.; Kim, Y. J.; Krüger, R.; Lesage, S.; Markopoulou, K.; Mellick, G.; Morrison, K. E.; Puschmann, A.; Tan, E. K.; Crosiers, D.; Theuns, J.; Van Broeckhoven, C.; Wirdefeldt, K.; Wszolek, Z. K.; Elbaz, A.; Maraganore, D. M.; Yahalom, G.; Orlev, Y.; Cohen, O. S.; Kozlova, E.; Friedman, E.; Inzelberg, R.; Hassin-Baer, S. (2014)
      Objectives: To determine whether α-synuclein dinucleotide repeat (REP1) genotypes are associated with survival in Parkinson's disease (PD). Methods: Investigators from the Genetic Epidemiology of Parkinson's Disease ...

    • The Application of Multivariate Model-Building to Derive Predictive Biomarker Signatures in Parkinson's Disease Patients 

      Gunselman, S. J.; Woodford, T. M.; Bramwell, D. I.; Chase, B. A.; Tsintou, M.; Markopoulou, K. (2010)

    • Attractor Divergence as a Metric for Assessing Walking Balance 

      Kurz, M. J.; Markopoulou, K.; Stergiou, N. (2010)
      Individuals with Parkinson's disease and the aged have a high prevalence of falls. Since an increase in the number of falls is associated with physical and psychological harm, it is prudent that biomechanical metrics be ...

    • Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease 

      Markopoulou, K.; Dickson, D. W.; McComb, R. D.; Wszolek, Z. K.; Katechalidou, L.; Avery, L.; Stansbury, M. S.; Chase, B. A. (2008)
      Individuals with familial Parkinson's disease (PD) due to a monogenic defect can show considerable clinical and neuropathological variability. To identify factors underlying this variability, histopathological analysis was ...

    • Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: AN international consensus statement 

      Puschmann, A.; Brighina, L.; Markopoulou, K.; Aasly, J.; Chung, S. J.; Frigerio, R.; Hadjigeorgiou, G.; Kõks, S.; Krüger, R.; Siuda, J.; Wider, C.; Zesiewicz, T. A.; Maraganore, D. M. (2015)
      Parkinson disease (PD) is associated with a clinical course of variable duration, severity, and a combination of motor and non-motor features. Recent PD research has focused primarily on etiology rather than clinical ...

    • Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease 

      Golbe, L. I.; Di Iorio, G.; Markopoulou, K.; Athanassiadou, A.; Papapetropoulos, S.; Watts, R. L.; Vance, J. M.; Bonifati, V.; Williams, T. A.; Spychala, J. R.; Stenroos, E. S.; Johnson, W. G. (2007)
      Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S-transferase (GST) has detoxification and antioxidative functions. To screen genetic ...

    • Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: Large-scale collaborative study 

      Evangelou, E.; Maraganore, D. M.; Annesi, G.; Brighina, L.; Brice, A.; Elbaz, A.; Ferrarese, C.; Hadjigeorgiou, G. M.; Krueger, R.; Lambert, J. C.; Lesage, S.; Markopoulou, K.; Mellick, G. D.; Meeus, B.; Pedersen, N. L.; Quattrone, A.; Van Broeckhoven, C.; Sharma, M.; Silburn, P. A.; Tan, E. K.; Wirdefeldt, K.; Ioannidis, J. P. A. (2010)
      Early genome-wide association (GWA) studies on Parkinson's disease (PD) have not been able to yield conclusive, replicable signals of association, perhaps due to limited sample size. We aimed to investigate whether association ...

    • Olfaction in Parkin-associated Parkinson disease 

      Markopoulou, K.; Chase, B. A. (2011)

    • Patterns of cognitive impairment in neurological disease 

      Markopoulou, K. (2010)
      Cognitive impairment is present in neurodegenerative disease, usually as part of a spectrum of symptoms that includes different domains of cognitive function. While the nature of the cognitive impairment tends to be ...

    • A Swedish family with de novo alpha-synuclein A53T mutation: Evidence for early cortical dysfunction 

      Puschmann, A.; Ross, O. A.; Vilarino-Guell, C.; Lincoln, S. J.; Kachergus, J. M.; Cobb, S. A.; Lindquist, S. G.; Nielsen, J. E.; Wszolek, Z. K.; Farrer, M.; Widner, H.; van Westen, D.; Hagerstrom, D.; Markopoulou, K.; Chase, B. A.; Nilsson, K.; Reimer, J.; Nilsson, C. (2009)
      A de novo alpha-symaclein A53T (p.Ala53 Th; c.209G > A) mutation has been identified in a Swedish family with autosomal dominant Parkinson's disease (PD). Two affected individuals had early-onset (before 31 and 40 years), ...